Paternally expressed gene 10 (PEG10) is a human retrotransposon-derived imprinted gene.Previous works have demonstrated that a mutation in the coding sequence of this gene is lethal with regard cinderella curtsy to embryological age due to defects of placental development.In addition, PEG10 is implicated in several malignancies, such as pancreatic

Dissection of the genetic architecture of complex traits persists as a major challenge in biology; despite considerable efforts, much remains unclear including the role and importance of genetic interactions.This study provides empirical evidence for a strong and persistent contribution of both second- and third-order epistatic interactions to long

Background: Chemokines are a family of proteins mainly mediating the homing and migration of various cells.The CXC chemokine CXCL12 is a member of low-weight-molecular chemokines.In the kidney, CXCL12 is pivotal for renal development and exerts a modulatory effect in kidney diseases under demonhorns edge different etiologic settings by binding with